Product Specifications: Lyophilized Powder (>99% purity) in 3ml vial. *Requires Reconstitution ** Available for bulk custom order with 57 Cap/Crimp colors to choose from.
Application: Research peptide studied for skin pigmentation and tanning, skin cancer prevention, photoprotection, and erectile dysfunction.
Chemical Formula: C78H111N21O19
CAS Number: 75921-69-6
Molecular Weight: ~1646.87 g/mol
Concentration: ≥99%
Melanotan-1 has gained significant attention in scientific research due to its unique mechanism of action and potential therapeutic benefits. As a synthetic analog of alpha-melanocyte stimulating hormone (α-MSH), it interacts with melanocortin receptors, which are involved in various physiological processes including pigmentation, inflammation, and immune response regulation.
Primary Research Applications
- Skin Pigmentation and Tanning
Research on melanotan-1 shows promising results for its ability to induce skin darkening and tanning through increased melanin production. Clinical trials have demonstrated efficacy in achieving darker skin tones without exposure to harmful UV radiation. This application could benefit individuals with photosensitivity disorders or those seeking to achieve tanned skin while minimizing sun exposure.
- Photoprotection and Skin Cancer Prevention
A significant focus of melanotan-1 research is its potential photoprotective effects. Studies suggest that by increasing melanin production, melanotan-1 may enhance the skin's natural defense against ultraviolet radiation, potentially reducing the risk of skin damage and skin cancers associated with UV exposure. This preventative application could be particularly valuable for high-risk populations.
- Inflammatory and Immune Disorders
The anti-inflammatory properties of melanotan-1 are being investigated for potential therapeutic applications in treating various skin conditions. Current research explores its efficacy in managing:
- Psoriasis
- Vitiligo
- Other inflammatory skin disorders
The peptide's interaction with melanocortin receptors may help regulate inflammatory processes and immune responses, offering new treatment avenues for these often difficult-to-treat conditions.
- Erectile Dysfunction
Although described as being in early research stages, melanotan-1 is also being studied for its potential in treating erectile dysfunction. This application stems from the peptide's interaction with melanocortin receptors that may influence sexual function, though this research area requires further development and clinical evaluation.
Mechanism of Action
Melanotan-1 functions primarily by activating the MC1 receptor, which plays a crucial role in:
- Regulating skin pigmentation
- Modulating inflammatory responses
- Influencing immune system function
References:
Dorr, R. T., Ertl, G., Levine, N., Brooks, C., Bangert, J. L., Powell, M. B., Humphrey, S., & Alberts, D. S. (2004). Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers. Archives of Dermatology, 140(7), 827-835. doi: 10.1001/archderm.140.7.827
Ugwu, S. O., Blanchard, J., Dorr, R. T., Levine, N., Brooks, C., Hadley, M. E., Aickin, M., & Hruby, V. J. (1997). Skin pigmentation and pharmacokinetics of melanotan-I in humans. Biopharmaceutics and Drug Disposition, 18(3), 259-269.
Hadley, M. E., & Dorr, R. T. (2006). Melanocortin peptide therapeutics: Historical milestones, clinical studies and commercialization. Peptides, 27(4), 921-930.
Disclaimer: This product is intended solely for laboratory research purposes. It is not suitable for consumption by humans, nor for medical, veterinary, or household purposes. Researchers should handle all peptides with care and adhere to strict safety guidelines during experiments. Only qualified professionals with appropriate expertise should manage and handle this product. The distributor, manufacturer, and seller of this product are not responsible for misuse or any resulting consequences. By accessing this product, you consent to comply with these terms and conditions.
