Product Specifications: Lyophilized Powder (>99% purity) in 3ml vial. *Requires Reconstitution ** Available for bulk custom order with 57 Cap/Crimp colors to choose from.
Application: Research peptide evaluated in anti-aging, neurological conditions, and cancer treatment. Clinical trials and laboratory studies continue to reveal new potential applications, making it a promising compound for various medical applications.
Chemical Formula: C14H22N4O9
CAS Number: 307297-39-8
Molecular Weight: ~390.35 g/mol
Concentration: ≥99%
Epithalon, also known as Epitalon or AEDG peptide, is a tetrapeptide that was originally synthesized based on bovine pineal gland extract (Epithalamin) and later discovered naturally in the human pineal gland 1. This compound has become the subject of extensive research across multiple therapeutic areas.
Key Research Areas
1. Aging and Longevity
Epithalon shows significant potential in aging-related research:
- Increases telomerase activity and extends telomere length in somatic cells
- Demonstrates geroprotective effects through antioxidant properties
- Clinical studies show reduced mortality rates in long-term treatment
- Can help reduce biological age, as demonstrated in clinical applications
2. Neurological Applications
Research focuses on several neurological aspects:
- Shows neuroprotective effects for neurodegenerative conditions
- Potential applications in Alzheimer's disease and other forms of dementia
- Regulates neuronal differentiation gene expression
- Influences melatonin synthesis and pineal gland function
3. Cancer Research
Studies investigate epithalon's anti-cancer properties:
- Demonstrates ability to inhibit cancer cell growth
- Induces apoptosis in cancer cells
- Shows potential in experimental cancer prevention
4. Cardiovascular Health
Clinical research shows promising cardiovascular applications:
- Reduces mortality in older adults with cardiovascular disease
- Long-term observational studies demonstrate improved survival rates
5. Cellular and Reproductive Health
Research extends to cellular and reproductive functions:
- Enhances oocyte quality and health
- Protects against post-ovulatory aging
- Improves cellular function and hormonal stability
6. Immune System Function
Studies demonstrate immunomodulatory effects:
- Improves immune function in elderly subjects
- Enhances T-cell counts
- Shows potential in treating autoimmune conditions
7. Antioxidant Properties
Research explores protective mechanisms:
- Scavenges free radicals
- Reduces oxidative damage to cells and tissues
- Demonstrates DNA protective properties
References:
Khavinson, V. K., & Kuznik, B. I. (2014). Peptide bioregulators: A new class of geroprotectors. Message 1: Results of experimental studies. Advances in Gerontology, 4(4), 298-301. https://doi.org/10.1134/S2079057014040080
Korkushko, O. V., Khavinson, V. K., Shatilo, V. B., & Antonyuk-Shcheglova, I. A. (2011). Peptide geroprotector from the pituitary gland inhibits rapid aging of elderly people: Results of 15-year follow-up. Bulletin of Experimental Biology and Medicine, 151(3), 366-369. https://doi.org/10.1007/s10517-011-1332-x
Lin'kova, N. S., Drobintseva, A. O., Orlova, O. A., Kuznetsova, E. P., Polyakova, V. O., Kvetnoy, I. M., & Khavinson, V. K.h (2016). Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro. Bulletin of experimental biology and medicine, 161(1), 175–178. https://doi.org/10.1007/s10517-016-3370-x
Disclaimer: This product is intended solely for laboratory research purposes. It is not suitable for consumption by humans, nor for medical, veterinary, or household purposes. Researchers should handle all peptides with care and adhere to strict safety guidelines during experiments. Only qualified professionals with appropriate expertise should manage and handle this product. The distributor, manufacturer, and seller of this product are not responsible for misuse or any resulting consequences. By accessing this product, you consent to comply with these terms and conditions.
