Application: Research peptide evaluated in healing, gastrointestinal health, neurology, cosmetics, organ protection, MS, and longevity
Chemical Formula: C62H98N16O22
CAS Number: 137525-51-0
Molecular Weight: ~1419.5 g/mol
Concentration: ≥99%
BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide being extensively researched for its diverse therapeutic applications. This report summarizes the key areas where BPC-157 is currently under investigation.
Primary Research Areas
1. Wound Healing and Tissue Regeneration
BPC-157 shows significant promise in wound healing through several mechanisms:
- Promotes cell proliferation, differentiation, and migration
- Enhances blood vessel formation through the VEGFR2-Akt-eNOS pathway
- Accelerates collagen reformation and tissue repair
2. Gastrointestinal Health
Research shows BPC-157's potential in treating various gastrointestinal conditions:
- Treatment of ulcerative colitis (Phase II clinical trials)
- Protection against stomach ulcerations
- Resolution of duodenal/colon lesions
- Treatment of inflammatory bowel disease (IBD)
3. Musculoskeletal System
Studies indicate benefits for:
- Tendon and ligament healing
- Muscle repair and regeneration
- Enhancement of growth hormone receptor expression in tendon fibroblasts
4. Neuroprotection
Research demonstrates potential applications in:
- Treatment of neurological conditions including multiple sclerosis
- Protection against hippocampal ischemia-reperfusion injuries
- Reduction of neuronal damage
5. Organ Protection
Recent studies explore BPC-157's protective effects on:
- Liver function
- Kidney health
- Lung tissue protection
- Protection against distant organ damage during ischemia-reperfusion injury
Current Clinical Status
Human Studies
- Limited but encouraging clinical evidence exists
- No toxicity reported in clinical trials
- Recent pilot study (2024) investigating effects on interstitial cystitis in women
- Not yet approved for human clinical use
Safety and Development
- Shows high efficacy in animal models, particularly rats
- No lethal dose (LD1) identified in toxicology studies
- Currently prohibited for athlete use by anti-doping agencies
Future Research Directions
- Expanded applications in tissue healing
- Potential neurological treatments
- Gastrointestinal therapeutic applications
- Organ protection mechanisms
References:
Gwyer, D., Wragg, N. M., & Wilson, S. L. (2019) conducted a systematic review examining BPC-157's effects on tendon healing. This comprehensive review has become a fundamental reference for understanding the peptide's role in musculoskeletal repair and regeneration.
Sikiric et al. (2018) investigated BPC-157's therapeutic potential in treating colitis and colon cancer. Their research provided valuable insights into the peptide's application in gastrointestinal disorders, demonstrating its effectiveness in treating ulcerative colitis and its potential anti-cancer properties.
Chang, C. H., Tsai, W. C., Hsu, Y. H., & Pang, J. H. (2017) explored the molecular mechanisms behind BPC-157's healing properties. Their research specifically focused on how the peptide enhances tendon healing through increased collagen synthesis and reduced inflammation.
Disclaimer: This product is intended solely for laboratory research purposes. It is not suitable for consumption by humans, nor for medical, veterinary, or household purposes. Researchers should handle all peptides with care and adhere to strict safety guidelines during experiments. Only qualified professionals with appropriate expertise should manage and handle this product. The distributor, manufacturer, and seller of this product are not responsible for misuse or any resulting consequences. By accessing this product, you consent to comply with these terms and conditions.
